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Glutamate Receptor 1 anticorps (pSer831)

Cet anticorps anti-Glutamate Receptor 1 est un anticorps Lapin Polyclonal détectant Glutamate Receptor 1 dans WB. Adapté pour Humain, Rat, Souris, Poulet et Chien.
N° du produit ABIN319113

Aperçu rapide pour Glutamate Receptor 1 anticorps (pSer831) (ABIN319113)

Antigène

Voir toutes Glutamate Receptor 1 (GLUR1) Anticorps
Glutamate Receptor 1 (GLUR1)

Reactivité

  • 120
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  • 1
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Humain, Rat, Souris, Poulet, Chien

Hôte

  • 132
  • 26
  • 1
  • 1
Lapin

Clonalité

  • 114
  • 46
Polyclonal

Conjugué

  • 77
  • 9
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Glutamate Receptor 1 est non-conjugé

Application

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  • 1
Western Blotting (WB)
  • Épitope

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    pSer831

    Specificité

    This antibody is specific for glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.

    Purification

    Affinity chromatography

    Immunogène

    Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.

    Isotype

    IgG
  • Indications d'application

    Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    Glutamate Receptor 1 (GLUR1)

    Autre désignation

    Glutamate Receptor 1 / GLUR1

    Sujet

    GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

    ID gène

    2890

    NCBI Accession

    NP_000818

    UniProt

    P42261

    Pathways

    Signalisation PI3K-Akt
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